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During radial migration, neurons follow a trajectory that is perpendicular to the ventricular surface, moving alongside radial glial fibers expanding the thickness of the neural tube. In contrast, tangentially migrating neurons move in trajectories that are parallel to the ventricular surface and orthogonal to the radial glia palisade
10 Oct 2004 To examine the mechanisms underlying glial-guided migration, we analyzed the dynamics of cytoskeletal and signaling components in living neurons. Diagnostic Imaging/methods; Dynactin Complex; Genetic Vectors/physiology; Glial Fibrillary Acidic Protein/metabolism; Green Fluorescent Proteins/
1 Jan 2002 In this review we shall discuss the current understanding of neuronal migration in the developing cerebral cortex, the evaluation of these patients, and attempt to describe .. The band of grey matter correlates with that seen by imaging. . Mechanisms of glial-guided neuronal migration in vitro and in vivo.
19 Feb 2011
2 Sep 2013 Neuron migrations are broadly classified as radial (parallel to RG) or tangential (orthogonal to RG, either around the circumference of the neural tube or along its length). Radial migrations include the glial-guided locomotion phase and glia-independent somal translocation phase of cortical projection
Neuronal migration is the method by which neurons travel from their origin or birthplace to their final position in the brain. There are several ways they can do this, e.g. by radial migration or tangential migration. This time lapse displays sequences of radial migration (also known as glial guidance) and somal translocation.
Interestingly, an earlier study using Golgi staining also suggested a mechanism for radially migrating neurons in the developing opossum cortex that is independent of glial guidance (Morest, 1970). In this mode, termed
Ann N Y Acad Sci. 1991;633:113-21. Molecular mechanisms of glial-guided neuronal migration. Stitt TN(1), Gasser UE, Hatten ME. Author information: (1)Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, New York, New York 10032. The migration of young neurons from their
Trends Neurosci. 1990 May;13(5):179-84. Riding the glial monorail: a common mechanism for glial-guided neuronal migration in different regions of the developing mammalian brain. Hatten ME(1). Author information: (1)Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, NY
     

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